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Scientific Software Developer

Carlsbad, CA

Ionis Pharmaceuticals, Inc., is headquartered in Carlsbad, California, with offices in Boston, Massachusetts, and Dublin, Ireland. For more than 30 years, Ionis has been the leader in RNA-targeted therapy, pioneering new markets and changing standards of care with our novel antisense technology. Ionis currently has three marketed medicines and a premier late-stage pipeline highlighted by industry-leading cardiovascular and neurological franchises.

Our scientific innovation began and continues with the knowledge that sick people depend on us, which fuels our vision to become the undisputed leader in genetic medicine, utilizing a multi-platform approach to discover, develop and deliver life-transforming therapies.

As the first company to fully harness the power of RNA technology for human therapeutics, Ionis’ platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. 

We are building upon our innovative research and drug development excellence to provide greater value to patients, and we are well positioned financially to deliver on our strategic goals.

Ionis is a challenging, motivating and rewarding environment designed to foster innovation and scientific excellence. 

Our success is a direct result of our outstanding employees. 

We are interested in bringing together a diverse group of individuals with different skill sets and perspectives into this creative environment to be part of a productive and inclusive team. While acknowledging people are actively engaged in hybrid/remote work, we continue to invest time, money, and energy into making our workplace locations a place where our culture and employees can thrive. 

We believe engaging on a day-to-day basis, in person, builds solid and lasting relationships, and contributes positively to our culture and innovation. From the heart of our stunning Carlsbad campus, we aim to provide a central connection point for all our employees. These facilities give us the opportunity to connect cross-functionally, collaborate and to build on the success of our business as we continue to grow.  Join us and experience our unique culture while you develop and expand your career.


We are seeking a highly qualified individual with relevant experience for a position in our research toxicology and informatics group, who shares the passion of our core principles and culture. Successful candidates will be skilled in analytical/quantitative thinking and knowledgeable in the development of scientific software. As a scientific software developer, your mission is to create, grow, and improve software resources that enable sustained improvement of the Ionis drug platform.

The selected candidate will work as part of a multidisciplinary and highly innovative team designing and implementing tools to support our drug discovery efforts. Work will include building cloud-based data and API services and delivering rich data-driven user-interfaces for the interrogation of complex biological and chemical datasets. So, join us and experience our unique culture while developing and expanding your career.


  • Maintain and optimizing the current software infrastructure essential for supporting in vivo research and development activities. This includes overseeing data management systems and ensuring scalability to accommodate expanding projects 
  • Develop new software tools for various research teams (medicinal chemists, biologists, computational biologists, and toxicologists) that aid in data capture and improves the use of internal and external data sources
  • Enhance data access using tools like RESTful API’s and modern web UI/UX frameworks
  • Work with end-users to troubleshoot and/or design and prioritize feature enhancements to existing tools


  • Bachelor’s Degree; advanced degree in related field preferred 
  • At least 3+ years software development experience 
  • Experience using version control systems and project management tools (Git and Jira) 
  • Proficient with modern programming languages (JavaScript, Python, or Java) 
  • Knowledge of modern web frameworks (Angular, Express, or React) 
  • Experience with relational (Postgres, Oracle SQL) and non-relational (DynamoDB) databases
  • Strong Linux skills 
  • Must have excellent communication and requirement gathering skills 
  • An ability to be productive and successful in an intense work environment
  • Able to learn new technologies quickly and jump in anywhere in our stack


  • Experience building UX/UI wireframes 
  • Experience in data mining methods and machine learning algorithms
  • Experience with bioinformatics and genomics is a big plus
  • Experience deploying services using AWS services and Docker
  • Experience with software test automation


The pay scale for this position is $96,090 to $141,600


Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.

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