Scientific Director - Project Toxicologist

Los Angeles, CA

If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of.

What you will do

Let’s do this. Let’s change the world. In this vital role, you will be the key scientific interface between Translational Safety & Bioanalytical Sciences (TS&BA) and your project teams from discovery through post-marketing.

The TS&BA function at Amgen is seeking a Scientific Director to serve as a Project Team Representative (PTR) and a Subject Matter Expert (SME), reporting to the Executive Director US Head Translational Safety and Bioanalytical Sciences Portfolio Scientific Leadership.

You will develop and implement fit-for-purpose nonclinical safety strategies based on a strong scientific foundation, flexibly evolve the strategy in response to team goals and emerging data and lead or influence multidisciplinary teams. As TS&BA PTR, you will partner with Project Teams developing therapeutics using multiple modalities (including biotherapeutics, small molecules and RNA therapies) to treat diseases in inflammation, cardiometabolic diseases, and/or oncology. TS&BA PTRs are encouraged to develop subject matter expertise related to a specific therapeutic area (e.g., obesity, dyslipidemia, etc.), modality, or safety concern. As an SME, you will provide advice, mentorship and support including at relevant occurrences of the TS&BA Portfolio Scientific Advisory Committee.

The successful candidate will have:

A sustained track record of scientific leadership as well as in preclinical development with a strong understanding of cross-functional needs and the ability to develop integrated plans to enable successful development of a therapeutic.
Organizational management and leadership experience including leadership of multi-disciplinary teams, leadership of critical initiatives and managing through organizational change.
Deep expertise in stages of development preceding First-in-Human with a passion for biological understanding and application of biological insights to program success.
Experience developing therapeutics of various modalities, e.g., small and large molecules, including fit-for-purpose study designs and selection of nonclinical species.
Working knowledge of GLP regulation and regulatory guidelines.
Prior work experience at, or collaborating with, contract research organizations.
Interest and ability to serve as a Subject Matter Expert in a specific area.
Excellent and professional verbal and written communication skills; proven ability to influence a broad spectrum of partners toward achieving business goals.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Basic Qualifications:

Doctorate degree and 4 years of Toxicology, Pharmacology or other related field.
Or Master’s degree and 7 years of Toxicology, Pharmacology or other related field.
Or Bachelor’s degree and 9 years of Toxicology, Pharmacology or other related field.

Preferred Qualifications:

10 years of drug development experience including interactions with regulatory agencies.
Prior experience with discovery and development of therapeutics for the treatment of cardiometabolic disorders (e.g., obesity).

Thrive

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

The annual base salary range for this opportunity in the U.S. is $187,090 - $214,547. In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans and bi-annual company-wide shutdowns
Flexible work models, including remote work arrangements, where possible