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Executive Director / Director, Pricing & Contracting

Remote (United States)

Ionis Pharmaceuticals, Inc., is headquartered in Carlsbad, California, with offices in Boston, Massachusetts, and Dublin, Ireland. For more than 30 years, Ionis has been the leader in RNA-targeted therapy, pioneering new markets and changing standards of care with our novel antisense technology. Ionis currently has three marketed medicines and a premier late-stage pipeline highlighted by industry-leading cardiovascular and neurological franchises.

Our scientific innovation began and continues with the knowledge that sick people depend on us, which fuels our vision to become the undisputed leader in genetic medicine, utilizing a multi-platform approach to discover, develop and deliver life-transforming therapies.

As the first company to fully harness the power of RNA technology for human therapeutics, Ionis’ platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. We are building upon our innovative research and drug development excellence to provide greater value to patients, and we are well positioned financially to deliver on our strategic goals.

Ionis is a challenging, motivating and rewarding environment designed to foster innovation and scientific excellence. Our success is a direct result of our outstanding employees. We are interested in bringing together a diverse group of individuals with different skill sets and perspectives into this creative environment to be part of a productive and inclusive team. 

While acknowledging people are actively engaged in hybrid/remote work, we continue to invest time, money, and energy into making our workplace locations a place where our culture and employees can thrive. We believe engaging on a day-to-day basis, in person, builds solid and lasting relationships, and contributes positively to our culture and innovation. 

From the heart of our stunning Carlsbad campus, we aim to provide a central connection point for all our employees. These facilities give us the opportunity to connect cross-functionally, collaborate and to build on the success of our business as we continue to grow.  Join us and experience our unique culture while you develop and expand your career.

Ionis Pharmaceuticals is in the process of building and scaling its US commercial enterprise in preparation for its first ever independent launch. The next pivotal step in the company’s growth will be to install, within its US Market Access Leadership team, a strategic and operational market master in US Pricing & Contracting to step in as its inaugural Executive Director/Director Pricing & Contracting role. 

The Pricing & Contracting Head is a crucial role that is responsible for developing and executing strategic pricing and contracting strategies through all stages of IONIS’ product lifecycles to optimize patient access, brand value and overall competitive advantage.


The ideal candidate will:

  •  Serve as the functional owner for US Pricing & Contracting for IONIS’ US market access enterprise owning and developing the strategy, vision, and direction for the P&C capability as the company prepares for its first independent commercial launch. 
  •  Develop and implement pricing and contracting strategies for each brand that align with the company's overall commercial objectives
  •  Provides prognostic insight and advisoryship to senior leadership by staying abreast changes in the healthcare landscape that may compel IONIS to adjust pricing and contracting strategies accordingly
  •  Drive continuous improvement, innovation, and implementation of pricing and contracting processes and procedures
  •  Monitor market trends and competitor pricing strategies to inform decision making and ensure competitiveness in the market
  • Build an appropriate and scalable operating model leveraging 3rd party partnerships where appropriate to execute: Contract Analytics & Reporting, GTN Forecasting, Install Pricing Analytics capability, Contract Administration
  • Support accounting in conducting quarterly closes by forecasting discounts for reserve items
  • Government Pricing and State Transparency Reporting processes, pricing calculation validations
  • Ensure compliance with all applicable laws, regulations, and company policies related to pricing and contracting
  • Foster a culture of excellence, collaboration, and accountability within the team and across the organization upholding behavioral excellence standards that map to IONIS’ values
  • Lead, mentor and develop a team of professionals to ensure the timely and effective execution of pricing and contracting initiatives
  • Collaborate with cross-functional teams, including sales, marketing, and finance, to develop pricing and contracting strategies that support the fundamental to ensure successful product commercialization and optimal profitability
  • Prioritize, communicate, and present pricing and contracting updates and strategies to internal stakeholders and senior management so IONIS can achieve access and profitability goals
  • Represent the company in meetings and negotiations with external stakeholders to advocate for the company's pricing and contracting interests


  • Bachelor’s Degree in an analytical area of study (finance, accounting); MBA preferred
  • Deep expertise in building and owning pricing & contracting strategy capabilities in pharma/ biotech
  • Enterprise level market mastery in the analytical methodology and rigor to drive best in class execution of pricing and contracting analytics, including GTN forecasting
  • Experience and leadership in developing contract proposals (financial models, GTN implications, and ROI analysis for evaluation) and effective negotiation strategy
  • Strong knowledge of systems and reporting mechanisms that supports pharmaceutical contract administration across customers (payer, provider, government, SPs, etc)
  • Expert level knowledge of the pharmacy and medical benefits, Medicare (FFS and Managed), Medicaid, and Federal purchasing programs
  • Subject matter expertise on IRA and its financial risks and opportunities to organization
  • Excellent oral, written and presentation skills with the ability to explain complex concepts clearly to variety of audiences
  • Attention to detail and the ability to work individually, within a multi-disciplinary team, as well as with external partners and vendors.

The pay scale for this position is $191,763 to $274,040

The pay scale for the Director position is $191,763 to $248,779

The pay scale for the Executive Director position is $233,590 to $274,040.


Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.

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